The European Society of Gene and Cell Therapy (ESGCT) board honors Professor Seppo Ylä-Herttuala for his exceptional career achievements and has selected him as the winner of the 2023 ESGCT Outstanding Achievement Award. The award is the most prestigious award conferred by the ESGCT.
Professor Seppo Ylä-Herttuala's outstanding contributions to the field of gene therapy have had a profound impact on both basic science and potential human therapies. He has not only served as President of the ESGCT but has also been involved in various significant roles, such as board membership with the European Society of Cardiology and chairing the Biocenter of Kuopio and EU-EATRIS national network.
Professor Ylä-Herttuala has made pioneering contributions to cardiovascular gene therapy. In 1995, he led the way by applying adenoviral gene transfer to human arteries, improving myocardial perfusion through VEGF in phase I/II trials. His research revealed the value of promoter-targeted upregulating shRNAs and the vasculoprotective effects of VEGF, benefiting dialysis patients in a phase II trial. He also developed essential techniques like a perivascular gene delivery device and the cloning of a soluble scavenger receptor for hyperlipidemia treatment. Furthermore, his work shed light on the biology and signaling of VEGFs such as VEGF-B and VEGF-C/D in the heart. Under his leadership, eight phase I-III gene therapy trials have been conducted. These achievements have revolutionized gene therapy and advanced medical science significantly.
Furthermore, as the founder of Ark Therapeutics Ltd (now FinVector Ltd) and the founder and Chairman of the Board at Rokote Laboratories Finland Oy, Professor Ylä-Herttuala continues to play a crucial role in developing clinical GMP gene transfer vectors and nasal vaccines, contributing to advancements in the field of gene therapy and vaccine research.
For further information, visit European Society of Gene and Cell Therapy website: https://www.esgct.eu/post/seppo-yla-herttuala-winner-of-2023-outstanding-achievement-award
Our CEO, Tuija Keinonen, will give a presentation titled 'Rokote Approach for Nasal Vaccination' at the World Vaccine Congress Europe in Barcelona on Tuesday, October 17th, at 12:05 PM.
We are delighted to have this opportunity to discuss intranasal vaccines and the development status of our vaccine. We are more than happy to engage in a chat about collaboration possibilities and vaccine development during the event.
The World Vaccine Congress Europe is the largest and most established European meeting on vaccine R&D. Join us there!
Link to the event: https://www.terrapinn.com/conference/world-vaccine-congress-europe/index.stm
Rokote Laboratories Finland Oy's intranasal coronavirus vaccine has transitioned from the product development phase to the production phase
Following the completion of the research and development phase for Rokote Laboratories Finland Oy's FINCoVac 2.1 coronavirus vaccine in early summer, the vaccine has advanced to the next stage in the production process at a designated contract manufacturer. This marks a significant milestone in the vaccine's development.
Multi-stage Production of the Drug Batch
Rokote Laboratories Finland Oy's drug (vaccine) is vector-based, utilizing a safe adenovirus as a carrier. Within the virus vector, the DNA sequence of the coronavirus spike protein has been cloned. The GMP-level production process of the virus vector vaccine began with the preparation of a large virus bank called the Master Viral Seed Stock (MVSS). The virus bank has already been prepared by Rokote Laboratories Finland Oy's contract manufacturer in Belgium. The MVSS virus bank has been divided into multiple sub-banks and is stored at -80°C to ensure long-term viability. The MVSS serves as the starting material to produce production-scale drug batches, and it can be used to produce several hundred drug batches.